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10.1016/j.inat.2020.100822 http://scihub22266oqcxt.onion/10.1016/j.inat.2020.100822 C7347486!7347486!32835018     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32835018&cmd=llinks): Failed to open stream: HTTP request failed! 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Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs benefit effect |pdf=|usr=}}{{32835018}} gab.com Text Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs benefit effect JO: Interdiscip Neurosurg http://www.kidney.de/pget.php?&tw=1&pmid=32835018 #FOAvip Objective: The present short report summarizes some clinical characteristics of six patients affected by stroke while being on angiotensin-converting enzyme (ACE)2 inhibitors and angiotensin II receptor blockers (ARBs) before and during COVID-19. Methods: Medical charts and images of six patients affected by stroke while being on ACE-Is and ARBs therapy before and during COVID-19 outbreak in Lombardy region, Italy, were reviewed. Results: Three patients had a dural sinus thrombosis, whereas the remaining suffered by an arterial ischemia, which was a middle cerebral artery occlusion in one case, and a posterior-inferior cerebellar artery occlusion in the remaining two. All patients showed clinical features typical of SARS-CoV-2 infection and positive chest CT scan, and were treated with ACE-Is as needed. Hypercoagulability panel was negative in any case. A recovery was achieved in all cases, although in a variable manner. Conclusions: Whether or not and in which manner the pharmacomodulation of the renin-angiotensin system may had affect the clinical course of the reported six COVID-19 patients affected by stroke has to be still clarified. An urgent need of randomized clinical trials aimed to assess the safety profile and neuroprotective properties of ACE-Is and ARBs in COVID-19 patients diagnosed with stroke does exists. Twit Text FOAVip Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs benefit effect ????Interdiscip Neurosurg http://www.kidney.de/pget.php?&tw=1&pmid=32835018 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32835018 #FOAvip English Wikipedia <ref>{{Cite pmid|32835018}}</ref> Targeting of renin-angiotensin system in COVID-19 patients affected by stroke: Emerging concerns about detrimental vs benefit effect #MMPMID32835018 Luzzi S; Giotta Lucifero A; Marasco S; Del Maestro M; Bellantoni G; Gragnaniello C Interdiscip Neurosurg 2020[Dec]; 22 (ä): 100822 PMID32835018show ga Objective: The present short report summarizes some clinical characteristics of six patients affected by stroke while being on angiotensin-converting enzyme (ACE)2 inhibitors and angiotensin II receptor blockers (ARBs) before and during COVID-19. Methods: Medical charts and images of six patients affected by stroke while being on ACE-Is and ARBs therapy before and during COVID-19 outbreak in Lombardy region, Italy, were reviewed. Results: Three patients had a dural sinus thrombosis, whereas the remaining suffered by an arterial ischemia, which was a middle cerebral artery occlusion in one case, and a posterior-inferior cerebellar artery occlusion in the remaining two. All patients showed clinical features typical of SARS-CoV-2 infection and positive chest CT scan, and were treated with ACE-Is as needed. Hypercoagulability panel was negative in any case. A recovery was achieved in all cases, although in a variable manner. Conclusions: Whether or not and in which manner the pharmacomodulation of the renin-angiotensin system may had affect the clinical course of the reported six COVID-19 patients affected by stroke has to be still clarified. An urgent need of randomized clinical trials aimed to assess the safety profile and neuroprotective properties of ACE-Is and ARBs in COVID-19 patients diagnosed with stroke does exists. äTargeting of renin-angiotensin system in COVID-19 patients affected by(epmc).pdf DeepDyve Pubget Overpricing