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The use of corticosteroids for COVID-19 infection
#MMPMID34235424
Richards GA
; Feldman C
Afr J Thorac Crit Care Med
2020[]; 26
(3
): ? PMID34235424
show ga
The SARS-CoV-2 pandemic is continuing relentlessly in many parts of the world and
has resulted in the outpouring of literature on various aspects of the infection,
including studies and recommendations regarding the optimal treatment of infected
patients. Not surprisingly, the use of corticosteroids in the management of such
patients has featured prominently in many of these publications. There is
considerable debate in the literature as to the likely benefits, as well as the
potential detrimental effects of corticosteroid therapy in general viral
respiratory infections and, in particular, COVID-19 infections. While the
definitive answer may need to await the results of ongoing randomised, controlled
trials recent studies suggest that corticosteroid use in COVID-19 cases with
hypoxaemia may benefit from low-dose corticosteroid therapy.