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10.3390/ph13060111 http://scihub22266oqcxt.onion/10.3390/ph13060111 C7345688!7345688!32485996     free     free     free       Pharmaceuticals+(Basel) 2020 ; 13 (6): ä Nephropedia Template TP {{tp|p=32485996|t=2020. Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery |pdf=|usr=}}{{32485996}} gab.com Text Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery JO: Pharmaceuticals (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32485996 #FOAvip Five-membered 1,2,4-oxadiazole heterocyclic ring has received considerable attention because of its unique bioisosteric properties and an unusually wide spectrum of biological activities. Thus, it is a perfect framework for the novel drug development. After a century since the 1,2,4-oxadiazole have been discovered, the uncommon potential attracted medicinal chemists? attention, leading to the discovery of a few presently accessible drugs containing 1,2,4-oxadiazole unit. It is worth noting that the interest in a 1,2,4-oxadiazoles? biological application has been doubled in the last fifteen years. Herein, after a concise historical introduction, we present a comprehensive overview of the recent achievements in the synthesis of 1,2,4-oxadiazole-based compounds and the major advances in their biological applications in the period of the last five years as well as brief remarks on prospects for further development. Twit Text FOAVip Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery ????Pharmaceuticals (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32485996 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32485996 #FOAvip English Wikipedia <ref>{{Cite pmid|32485996}}</ref> Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery #MMPMID32485996 Biernacki K; Da?ko M; Ciupak O; Kubi?ski K; Rachon J; Demkowicz S Pharmaceuticals (Basel) 2020[Jun]; 13 (6): ä PMID32485996show ga Five-membered 1,2,4-oxadiazole heterocyclic ring has received considerable attention because of its unique bioisosteric properties and an unusually wide spectrum of biological activities. Thus, it is a perfect framework for the novel drug development. After a century since the 1,2,4-oxadiazole have been discovered, the uncommon potential attracted medicinal chemists? attention, leading to the discovery of a few presently accessible drugs containing 1,2,4-oxadiazole unit. It is worth noting that the interest in a 1,2,4-oxadiazoles? biological application has been doubled in the last fifteen years. Herein, after a concise historical introduction, we present a comprehensive overview of the recent achievements in the synthesis of 1,2,4-oxadiazole-based compounds and the major advances in their biological applications in the period of the last five years as well as brief remarks on prospects for further development. äNovel 1,2,4-Oxadiazole Derivatives in Drug Discovery (epmc).pdf DeepDyve Pubget Overpricing