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10.1016/j.ajem.2020.06.082

http://scihub22266oqcxt.onion/10.1016/j.ajem.2020.06.082
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C7335247!7335247!33071092
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suck abstract from ncbi


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pmid33071092      Am+J+Emerg+Med 2020 ; 38 (10): 2194-202
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  • Initial emergency department mechanical ventilation strategies for COVID-19 hypoxemic respiratory failure and ARDS #MMPMID33071092
  • Lentz S; Roginski MA; Montrief T; Ramzy M; Gottlieb M; Long B
  • Am J Emerg Med 2020[Oct]; 38 (10): 2194-202 PMID33071092show ga
  • Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging viral pathogen that causes the novel coronavirus disease of 2019 (COVID-19) and may result in hypoxemic respiratory failure necessitating invasive mechanical ventilation in the most severe cases. Objective: This narrative review provides evidence-based recommendations for the treatment of COVID-19 related respiratory failure requiring invasive mechanical ventilation. Discussion: In severe cases, COVID-19 leads to hypoxemic respiratory failure that may meet criteria for acute respiratory distress syndrome (ARDS). The mainstay of treatment for ARDS includes a lung protective ventilation strategy with low tidal volumes (4?8 mL/kg predicted body weight), adequate positive end-expiratory pressure (PEEP), and maintaining a plateau pressure of < 30 cm H2O. While further COVID-19 specific studies are needed, current management should focus on supportive care, preventing further lung injury from mechanical ventilation, and treating the underlying cause. Conclusions: This review provides evidence-based recommendations for the treatment of COVID-19 related respiratory failure requiring invasive mechanical ventilation.
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