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Characteristics, risk factors and outcomes among the first consecutive 1096
patients diagnosed with COVID-19 in Kuwait
#MMPMID32766546
Almazeedi S
; Al-Youha S
; Jamal MH
; Al-Haddad M
; Al-Muhaini A
; Al-Ghimlas F
; Al-Sabah S
EClinicalMedicine
2020[Jul]; 24
(?): 100448
PMID32766546
show ga
BACKGROUND: In Kuwait, prior to the first case of COVID-19 being reported in the
country, mass screening of incoming travelers from countries with known outbreaks
was performed and resulted in the first identified cases in the country. All
COVID-19 cases at the time and subsequently after, were transferred to a single
center, Jaber Al-Ahmad Al-Sabah Hospital, where the patients received
standardized investigations and treatments. The objective of this study was to
characterize the demographics, clinical manifestations, and outcomes in this
unique patient population. METHODS: This retrospective cohort study was conducted
between 24th February 2020 and 20th April 2020. All consecutive patients in the
entire State of Kuwait diagnosed with COVID-19 according to WHO guidelines and
admitted to Jaber Al-Ahmad Al-Sabah Hospital were included. Patients received
standardized investigations and treatments. Multivariable analysis was used to
determine the associations between risk factors and outcomes (admission to
intensive care and/or mortality). FINDINGS: Of 1096 patients, the median age was
41 years and 81% of patients were male. Most patients were asymptomatic on
admission (46.3%), of whom 35 later developed symptoms, and 59.7% had no signs of
infection. Only 3.6% of patients required an ICU admission and 1.7% were dead at
the study's cutoff date. On multivariable analysis, the risk factors found to be
significantly associated with admission to intensive care were age above 50 years
old, a qSOFA score above 0, smoking, elevated CRP and elevated procalcitonin
levels. Asthma, smoking and elevated procalcitonin levels correlated
significantly with mortality in our cohort.