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2020 ; 53
(ä): 101636
Nephropedia Template TP
gab.com Text
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English Wikipedia
Aptamers, the bivalent agents as probes and therapies for coronavirus infections:
A systematic review
#MMPMID32634550
Torabi R
; Ranjbar R
; Halaji M
; Heiat M
Mol Cell Probes
2020[Oct]; 53
(ä): 101636
PMID32634550
show ga
The recently known coronavirus, SARS-CoV-2, has turn into the greatest global
health challenge, affecting a large number of societies. The lack of specific
treatment and gold-standard diagnostic system has made the situation more
complicated. Efforts have led to production of several diagnostic kits that are
associated with limitations such as inadequate sensitivity and accuracy. Aptamers
as multipotent biological probes could be promising candidates to design
sensitive and specific biosensors. Although few studies have introduced specific
aptamer types of coronavirus, they may help us select the best approach to obtain
specific aptamers for this virus. On the other hand, some of already-introduced
aptamers have shown the inhibitory effects on coronavirus that could be applied
as therapeutics. The present study has provided a systematic overview on use of
aptamer-based biosensors and drugs to diagnose and treat coronavirus.
|*Biosensing Techniques
[MESH]
|Antiviral Agents/metabolism/*therapeutic use
[MESH]
|Aptamers, Nucleotide/metabolism/*therapeutic use
[MESH]