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COVID-19: Clinical aspects and therapeutics responses
#MMPMID32788835
Khan S
; Ali A
; Shi H
; Siddique R
; Shabana
; Nabi G
; Hu J
; Wang T
; Dong M
; Zaman W
; Han G
Saudi Pharm J
2020[Aug]; 28
(8
): 1004-1008
PMID32788835
show ga
COVID-19 has created havoc in the world by causing thousands of demises in a
short period of time. Up till now, several attempts have been made for potential
therapeutics against SARS-COV2. In this retrospective, single-center study, we
extracted data from 122 COVID-19, RT-PCR confirmed patients. who were treated
with a new treatment strategy of lianhuaqingwen with Arbidol Hydrochloride. The
patients were either asymptomatic or had mild symptoms for COVID-19 disease. Of
122 patients 21 (17.21%) patients developed severe conditions of COVID-19, while
total 111 (90.9%) experienced mild symptoms such as fever in 93 (76.22%)
patients, cough in 23 (20.17%) and muscle pain were observed in total 8 (7%)
patients. Furthermore our newly applied drugs combination (Lianhuaqingwen and
Arbidol Hydrochloride) showed therapeutic effects in 5-7 days in patients with
mild symptoms with 98% recovery rate. These results indicate that COVID-19
patients with mild symptoms can be treated with Lianhuaqingwen and Arbidol
Hydrochloride. However, extensive clinical investigations are required to confirm
the effectiveness of these drugs.