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2020 ; 59
(5
): 102866
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First case of convalescent plasma transfusion in a child with COVID-19-associated
severe aplastic anemia
#MMPMID32636116
Figlerowicz M
; Mania A
; Lubarski K
; Lewandowska Z
; S?u?ewski W
; Derwich K
; Wachowiak J
; Mazur-Melewska K
Transfus Apher Sci
2020[Oct]; 59
(5
): 102866
PMID32636116
show ga
We present the case of a six-year-old girl with severe COVID-19, in whom
SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion.
Children show a variable clinical course of COVID-19, from asymptomatic to
critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with
severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic
anemia remains unclear. At the beginning of the disease, we used antiviral drugs
and immune modulators as therapy but without any positive results. After
providing a transfusion of convalescent plasma, the elimination of SARS-CoV-2 was
observed. We did not observe any adverse events of this treatment. The girl still
has a diagnosis of aplastic anemia and requires specialist therapy.