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10.1016/j.dsx.2020.06.060

http://scihub22266oqcxt.onion/10.1016/j.dsx.2020.06.060
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suck abstract from ncbi


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pmid32668401
      Diabetes+Metab+Syndr 2020 ; 14 (5 ): 1149-1151
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  • BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: Preliminary findings from UK biobank #MMPMID32668401
  • Sattar N ; Ho FK ; Gill JM ; Ghouri N ; Gray SR ; Celis-Morales CA ; Katikireddi SV ; Berry C ; Pell JP ; McMurray JJ ; Welsh P
  • Diabetes Metab Syndr 2020[Sep]; 14 (5 ): 1149-1151 PMID32668401 show ga
  • AIMS: We examined the link between BMI and risk of a positive test for SARS-CoV-2 and risk of COVID-19-related death among UK Biobank participants. METHODS: Among 4855 participants tested for SARS-CoV-2 in hospital, 839 were positive and of these 189 died from COVID-19. Poisson models with penalised thin plate splines were run relating exposures of interest to test positivity and case-fatality, adjusting for confounding factors. RESULTS: BMI was associated strongly with positive test, and risk of death related to COVID-19. The gradient of risk in relation to BMI was steeper in those under 70, compared with those aged 70 years or older for COVID-19 related death (P(interaction) = 0.03). BMI was more strongly related to test positivity (P(interaction) = 0.010) and death (P(interaction) = 0.002) in non-whites (predominantly South Asians and Afro-Caribbeans), compared with whites. CONCLUSIONS: These data add support for adiposity being more strongly linked to COVID-19-related deaths in younger people and non-white ethnicities. If future studies confirm causality, lifestyle interventions to improve adiposity status may be important to reduce the risk of COVID-19 in all, but perhaps particularly, non-white communities.
  • |*Body Mass Index [MESH]
  • |Age Factors [MESH]
  • |Betacoronavirus/*isolation & purification [MESH]
  • |Biological Specimen Banks/*statistics & numerical data [MESH]
  • |COVID-19 [MESH]
  • |Coronavirus Infections/epidemiology/*mortality/transmission/*virology [MESH]
  • |Ethnicity/*statistics & numerical data [MESH]
  • |Humans [MESH]
  • |Pandemics [MESH]
  • |Pneumonia, Viral/epidemiology/*mortality/transmission/*virology [MESH]
  • |Prognosis [MESH]
  • |Risk Factors [MESH]
  • |SARS-CoV-2 [MESH]
  • |Sex Factors [MESH]
  • |Survival Rate [MESH]


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