Bleeding pneumonia: Diffuse alveolar hemorrhage due to human metapneumovirus
#MMPMID32665889
Rodriguez-Nava G
; Shrestha E
; Upadhyay B
; Morante A
; Joseph D
; Suhail A
; Trelles-Garcia DP
; Yanez-Bello MA
IDCases
2020[]; 21
(?): e00894
PMID32665889
show ga
Diffuse alveolar hemorrhage is a condition with high morbidity and mortality. The
majority of cases are caused by pulmonary capillaritis associated with systemic
vasculitis. Infection disease has also been associated with this condition. A
62-year-old woman with a history of chronic alcohol abuse presented with
shortness of breath, hemoptysis, constipation, and icterus. Chest x-rays on
admission showed diffuse patchy opacities concerning for diffuse alveolar
hemorrhage. The patient quickly developed acute respiratory failure requiring
intubation. PCR identified human metapneumovirus and bronchoalveolar lavage
confirmed alveolar hemorrhage. Despite all efforts, the patient ultimately
developed multi-organ failure and died. Human metapneumovirus is usually
associated with mild upper and lower respiratory tract infections in young
children. Nevertheless, clinicians should recognize that this virus has recently
emerged as a significant pathogen, particularly in adult patients with underlying
conditions and the elderly population.