Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32834942
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Potential benefits of combination of Nigella sativa and Zn supplements to treat
COVID-19
#MMPMID32834942
Rahman MT
J Herb Med
2020[Oct]; 23
(?): 100382
PMID32834942
show ga
An effective vaccine to prevent the SARS-CoV-2 causing COVID-19 is yet to be
approved. Further there is no drug that is specific to treat COVID-19. A number
of antiviral drugs such as Ribavirin, Remdesivir, Lopinavir/ritonavir,
Azithromycin and Doxycycline have been recommended or are being used to treat
COVID-19 patients. In addition to these drugs, rationale and evidence have been
presented to use chloroquine to treat COVID-19, arguably with certain precautions
and criticism. In line with the proposed use of chloroquine, Nigella sativa
(black seed) could be considered as a natural substitute that contains a number
of bioactive components such as thymoquinone, dithymoquinone, thymohydroquinone,
and nigellimine. Further benefits to use N. sativa could be augmented by Zn
supplement. Notably, Zn has been proven to improve innate and adaptive immunity
in the course of any infection, be it by pathogenic virus or bacteria. The
effectiveness of the Zn salt supplement could also be enhanced with N. sativa as
its major bioactive component might work as ionophore to allow Zn2+ to enter
pneumocytes - the target cell for SARSCoV-2. Given those benefits, this review
paper describes how N. sativa in combination with Zn could be useful as a
complement to COVID-19 treatment.
free
free
free
