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10.1007/s00405-020-06131-3

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C7312102!7312102!32583183
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suck abstract from ncbi


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pmid32583183      Eur+Arch+Otorhinolaryngol 2020 ; 277 (10): 2783-92
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  • Ethyl alcohol threshold test: a fast, reliable and affordable olfactory Assessment tool for COVID-19 patients #MMPMID32583183
  • Calvo-Henriquez C; Maldonado-Alvarado B; Chiesa-Estomba C; Rivero-Fernández I; Sanz-Rodriguez M; Villarreal IM; Rodriguez-Iglesias M; Mariño-Sánchez F; Rivero-de-Aguilar A; Lechien JR; Martínez-Capoccioni G; Saussez S; Capasso R; Karkos PD; Schriever V; Martin-Martin C; Alobid I; Santamaría-Gadea A; Fragola C; Mayo-Yáñez M; Pérez-Freixo H; Ninchritz-Becerra E; Soriano-Reixach M; Mondragon-Rezola E; Ruiz-Coello Mdel MM; Navarro RA; García-Fernández A; Marchan-López Á
  • Eur Arch Otorhinolaryngol 2020[]; 277 (10): 2783-92 PMID32583183show ga
  • Objective: COVID-19 patients may present mild symptoms. The identification of paucisymptomatic patients is paramount in order to interrupt the transmission chain of the virus. Olfactory loss could be one of those early symptoms which might help in the diagnosis of COVID-19 patients. In this study, we aim to develop and validate a fast, inexpensive, reliable and easy-to-perform olfactory test for the screening of suspected COVID-19 patients. Study design: Phase I was a case?control study and Phase II a transversal descriptive study. Subjects and methods: Olfaction was assessed with the ethyl alcohol threshold test and symptoms with visual analogue scales. The study was designed in two phases: In Phase I, we compared confirmed COVID-19 patients and healthy controls. In Phase II, patients with suspected COVID-19 infection referred for testing were studied. Results: 275 participants were included in Phase I, 135 in Phase II. The ROC curve showed an AUC of 0.749 in Phase I, 0.737 in Phase II. The cutoff value which offered the highest amount of correctly classified patients was?? 2 (10% alcohol) for all age intervals. The odds ratio was 8.19 in Phase I, 6.56 in Phase II with a 75% sensitivity. When cases report normal sense of smell (VAS?
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