Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32572794
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 CNS+Drugs
2020 ; 34
(9
): 897-913
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Application of Healthcare Big Data in CNS Drug Research: The Example of the
Neurological and mental health Global Epidemiology Network (NeuroGEN)
#MMPMID32572794
Ilomäki J
; Bell JS
; Chan AYL
; Tolppanen AM
; Luo H
; Wei L
; Lai EC
; Shin JY
; De Paoli G
; Pajouheshnia R
; Ho FK
; Reynolds L
; Lau KK
; Crystal S
; Lau WCY
; Man KKC
; Brauer R
; Chan EW
; Shen CY
; Kim JH
; Lum TYS
; Hartikainen S
; Koponen M
; Rooke E
; Bazelier M
; Klungel O
; Setoguchi S
; Pell JP
; Cook S
; Wong ICK
CNS Drugs
2020[Sep]; 34
(9
): 897-913
PMID32572794
show ga
Neurological and psychiatric (mental health) disorders have a large impact on
health burden globally. Cognitive disorders (including dementia) and stroke are
leading causes of disability. Mental health disorders, including depression,
contribute up to one-third of total years lived with disability. The Neurological
and mental health Global Epidemiology Network (NeuroGEN) is an international
multi-database network that harnesses administrative and electronic medical
records from Australia, Asia, Europe and North America. Using these databases
NeuroGEN will investigate medication use and health outcomes in neurological and
mental health disorders. A key objective of NeuroGEN is to facilitate
high-quality observational studies to address evidence-practice gaps where
randomized controlled trials do not provide sufficient information on medication
benefits and risks that is specific to vulnerable population groups.
International multi-database research facilitates comparisons across geographical
areas and jurisdictions, increases statistical power to investigate small
subpopulations or rare outcomes, permits early post-approval assessment of safety
and effectiveness, and increases generalisability of results. Through bringing
together international researchers in pharmacoepidemiology, NeuroGEN has the
potential to be paradigm-changing for observational research to inform
evidence-based prescribing. The first focus of NeuroGEN will be to address
evidence-gaps in the treatment of chronic comorbidities in people with dementia.
|*Big Data
[MESH]
|Central Nervous System Agents/*pharmacology
[MESH]
|Databases, Factual
[MESH]
|Delivery of Health Care/organization & administration
[MESH]