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10.1016/j.jstrokecerebrovasdis.2020.105068

http://scihub22266oqcxt.onion/10.1016/j.jstrokecerebrovasdis.2020.105068
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suck abstract from ncbi


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pmid32807471
      J+Stroke+Cerebrovasc+Dis 2020 ; 29 (9 ): 105068
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  • Acute stroke care in a New York City comprehensive stroke center during the COVID-19 pandemic #MMPMID32807471
  • Agarwal S ; Scher E ; Rossan-Raghunath N ; Marolia D ; Butnar M ; Torres J ; Zhang C ; Kim S ; Sanger M ; Humbert K ; Tanweer O ; Shapiro M ; Raz E ; Nossek E ; Nelson PK ; Riina HA ; de Havenon A ; Wachs M ; Farkas J ; Tiwari A ; Arcot K ; Parella DT ; Liff J ; Wu T ; Wittman I ; Caldwell R ; Frontera J ; Lord A ; Ishida K ; Yaghi S
  • J Stroke Cerebrovasc Dis 2020[Sep]; 29 (9 ): 105068 PMID32807471 show ga
  • BACKGROUND AND PURPOSE: The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented demand and burden on emergency health care services in New York City. We aim to describe our experience providing acute stroke care at a comprehensive stroke center (CSC) and the impact of the pandemic on the quality of care for patients presenting with acute ischemic stroke (AIS). METHODS: We retrospectively analyzed data from a quality improvement registry of consecutive AIS patients at New York University Langone Health's CSC between 06/01/2019-05/15/2020. During the early stages of the pandemic, the acute stroke process was modified to incorporate COVID-19 screening, testing, and other precautionary measures. We compared stroke quality metrics including treatment times and discharge outcomes of AIS patients during the pandemic (03/012020-05/152020) compared with a historical pre-pandemic group (6/1/2019-2/29/2020). RESULTS: A total of 754 patients (pandemic-120; pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%) received alteplase and/or mechanical thrombectomy. Despite longer median door to head CT times (16 vs 12 minutes; p = 0.05) and a trend towards longer door to groin puncture times (79.5 vs. 71 min, p?=?0.06), the time to alteplase administration (36 vs 35 min; p?=?0.83), door to reperfusion times (103 vs 97 min, p?=?0.18) and defect-free care (95.2% vs 94.7%; p?=?0.84) were similar in the pandemic and pre-pandemic groups. Successful recanalization rates (TICI?2b) were also similar (82.6% vs. 86.7%, p?=?0.48). After adjusting for stroke severity, age and a prior history of transient ischemic attack/stroke, pandemic patients had increased discharge mortality (adjusted OR 2.90 95% CI 1.77 - 7.17, p?=?0.021) CONCLUSION: Despite unprecedented demands on emergency healthcare services, early multidisciplinary efforts to adapt the acute stroke treatment process resulted in keeping the stroke quality time metrics close to pre-pandemic levels. Future studies will be needed with a larger cohort comparing discharge and long-term outcomes between pre-pandemic and pandemic AIS patients.
  • |*Thrombectomy [MESH]
  • |*Thrombolytic Therapy [MESH]
  • |Aged [MESH]
  • |Aged, 80 and over [MESH]
  • |Betacoronavirus/*pathogenicity [MESH]
  • |COVID-19 [MESH]
  • |Comprehensive Health Care/*organization & administration [MESH]
  • |Coronavirus Infections/diagnosis/epidemiology/*therapy/virology [MESH]
  • |Critical Pathways/organization & administration [MESH]
  • |Delivery of Health Care, Integrated/*organization & administration [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |New York City/epidemiology [MESH]
  • |Pandemics [MESH]
  • |Patient Care Team/organization & administration [MESH]
  • |Pneumonia, Viral/diagnosis/epidemiology/*therapy/virology [MESH]
  • |Quality Improvement/*organization & administration [MESH]
  • |Quality Indicators, Health Care/*organization & administration [MESH]
  • |Registries [MESH]
  • |Retrospective Studies [MESH]
  • |SARS-CoV-2 [MESH]
  • |Stroke/diagnosis/epidemiology/*therapy [MESH]
  • |Time Factors [MESH]
  • |Time-to-Treatment/organization & administration [MESH]
  • |Treatment Outcome [MESH]


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