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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Stroke+Cerebrovasc+Dis
2020 ; 29
(9
): 105068
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Acute stroke care in a New York City comprehensive stroke center during the
COVID-19 pandemic
#MMPMID32807471
Agarwal S
; Scher E
; Rossan-Raghunath N
; Marolia D
; Butnar M
; Torres J
; Zhang C
; Kim S
; Sanger M
; Humbert K
; Tanweer O
; Shapiro M
; Raz E
; Nossek E
; Nelson PK
; Riina HA
; de Havenon A
; Wachs M
; Farkas J
; Tiwari A
; Arcot K
; Parella DT
; Liff J
; Wu T
; Wittman I
; Caldwell R
; Frontera J
; Lord A
; Ishida K
; Yaghi S
J Stroke Cerebrovasc Dis
2020[Sep]; 29
(9
): 105068
PMID32807471
show ga
BACKGROUND AND PURPOSE: The coronavirus disease-2019 (COVID-19) pandemic caused
unprecedented demand and burden on emergency health care services in New York
City. We aim to describe our experience providing acute stroke care at a
comprehensive stroke center (CSC) and the impact of the pandemic on the quality
of care for patients presenting with acute ischemic stroke (AIS). METHODS: We
retrospectively analyzed data from a quality improvement registry of consecutive
AIS patients at New York University Langone Health's CSC between
06/01/2019-05/15/2020. During the early stages of the pandemic, the acute stroke
process was modified to incorporate COVID-19 screening, testing, and other
precautionary measures. We compared stroke quality metrics including treatment
times and discharge outcomes of AIS patients during the pandemic
(03/012020-05/152020) compared with a historical pre-pandemic group
(6/1/2019-2/29/2020). RESULTS: A total of 754 patients (pandemic-120;
pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%)
received alteplase and/or mechanical thrombectomy. Despite longer median door to
head CT times (16 vs 12 minutes; p = 0.05) and a trend towards longer door to
groin puncture times (79.5 vs. 71 min, p?=?0.06), the time to alteplase
administration (36 vs 35 min; p?=?0.83), door to reperfusion times (103 vs
97 min, p?=?0.18) and defect-free care (95.2% vs 94.7%; p?=?0.84) were similar in
the pandemic and pre-pandemic groups. Successful recanalization rates (TICI?2b)
were also similar (82.6% vs. 86.7%, p?=?0.48). After adjusting for stroke
severity, age and a prior history of transient ischemic attack/stroke, pandemic
patients had increased discharge mortality (adjusted OR 2.90 95% CI 1.77 - 7.17,
p?=?0.021) CONCLUSION: Despite unprecedented demands on emergency healthcare
services, early multidisciplinary efforts to adapt the acute stroke treatment
process resulted in keeping the stroke quality time metrics close to pre-pandemic
levels. Future studies will be needed with a larger cohort comparing discharge
and long-term outcomes between pre-pandemic and pandemic AIS patients.
|*Thrombectomy
[MESH]
|*Thrombolytic Therapy
[MESH]
|Aged
[MESH]
|Aged, 80 and over
[MESH]
|Betacoronavirus/*pathogenicity
[MESH]
|COVID-19
[MESH]
|Comprehensive Health Care/*organization & administration
[MESH]