Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Allergy+Asthma+Clin+Immunol 2020 ; 16 (ä): ä Nephropedia Template TP
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Anaphylaxis to clindamycin following cutaneous exposure #MMPMID32577121
Paradis N; Marois L; Paradis L; Graham F; Bégin P; Des Roches A
Allergy Asthma Clin Immunol 2020[]; 16 (ä): ä PMID32577121show ga
Background: The role and importance of skin barrier as an immunologic organ and as a potent way of sensitization is well known. However, antibiotics anaphylaxis following skin sensitization has not been reported. Case presentation: We describe the first case of intravenous clindamycin anaphylaxis, with likely sensitization due to previous topical exposure to clindamycin gel for acne in a 14-year-old boy with history of atopy and mild atopic dermatitis. Conclusion: This case highlights the potential sensitization to drug allergens, including antibiotics, via the skin.