Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32912559
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Stroke and COVID19: Not only a large-vessel disease
#MMPMID32912559
Frisullo G
; Bellavia S
; Scala I
; Piano C
; Morosetti R
; Brunetti V
; Calabresi P
; Della Marca G
J Stroke Cerebrovasc Dis
2020[Oct]; 29
(10
): 105074
PMID32912559
show ga
Recent evidence has underlined the association between large-vessel stroke and
COVID-19, probably due to a proinflammatory and prothrombotic microenvironment
induced by SARS-CoV-2. Here, we report the case of a young fit woman affected by
COVID-19 without any flu-like symptom, who suffered from speech disorder and left
hemiparesis. Brain magnetic resonance evidenced two small acute brain infarctions
in right perirolandic cortex without signs of previous ischemic lesions and
hemorrhagic infarction. Diagnostic workup excluded cardiac embolic sources,
acquired and inherited thrombophilia or autoimmune diseases. Two positive
nasopharyngeal swab tests and high titers of serum specific IgA/IgM confirmed
COVID-19 diagnosis. In our case stroke seems to be the only manifestation of
SARS-COV-2 infection. Therefore the hypothesis of an underlying viral infection,
as COVID-19, should be investigated in all the cases of small vessel cryptogenic
stroke.
|Betacoronavirus/pathogenicity
[MESH]
|COVID-19
[MESH]
|Cerebral Small Vessel Diseases/diagnostic imaging/*etiology/virology
[MESH]
free
free
free
