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Thrombosis and COVID-19 pneumonia: the clot thickens! #MMPMID32554532
Price LC; McCabe C; Garfield B; Wort SJ
Eur Respir J 2020[Jul]; 56 (1): ä PMID32554532show ga
At the end of last year, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulted in an acute respiratory illness epidemic in Wuhan, China [1, 2]. The World Health Organization (WHO) termed this illness coronavirus disease 2019 (COVID-19). The coronavirus family have been shown to enter cells through binding angiotensin-converting enzyme 2 (ACE-2), found mainly on alveolar epithelium and endothelium. Activation of endothelial cells is thought to be the primary driver for the increasingly recognised complication of thrombosis.