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P-FAB: A Fiber-Optic Biosensor Device for Rapid Detection of COVID-19 #MMPMID38624432
Murugan D; Bhatia H; Sai VVR; Satija J
ä-/-ä 2020[]; 5 (2): 211-5 PMID38624432show ga
Rapid and low-cost diagnosis of COVID-19 is essential to identify the infected subjects, particularly the asymptomatic cases, primarily to arrest the spread of the disease through local transmission. Antibody-based chromatographic serological tests, as an alternative to RT-PCR, offer only limited help due to high false positives. We propose to exploit our field-deployable/portable plasmonic fiber-optic absorbance biosensor (P-FAB) platform for one-step, wash-free detection of SARS-CoV-2 virus particles directly in saliva sample with minimal sample pre-processing.