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10.1111/anae.15170

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C7300828!7300828 !32516833
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suck abstract from ncbi


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pmid32516833
      Anaesthesia 2020 ; 75 (11 ): 1437-1447
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  • Risks to healthcare workers following tracheal intubation of patients with COVID-19: a prospective international multicentre cohort study #MMPMID32516833
  • El-Boghdadly K ; Wong DJN ; Owen R ; Neuman MD ; Pocock S ; Carlisle JB ; Johnstone C ; Andruszkiewicz P ; Baker PA ; Biccard BM ; Bryson GL ; Chan MTV ; Cheng MH ; Chin KJ ; Coburn M ; Jonsson Fagerlund M ; Myatra SN ; Myles PS ; O'Sullivan E ; Pasin L ; Shamim F ; van Klei WA ; Ahmad I
  • Anaesthesia 2020[Nov]; 75 (11 ): 1437-1447 PMID32516833 show ga
  • Healthcare workers involved in aerosol-generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID-19. However, the magnitude of this risk is unknown. We conducted a prospective international multicentre cohort study recruiting healthcare workers participating in tracheal intubation of patients with suspected or confirmed COVID-19. Information on tracheal intubation episodes, personal protective equipment use and subsequent provider health status was collected via self-reporting. The primary endpoint was the incidence of laboratory-confirmed COVID-19 diagnosis or new symptoms requiring self-isolation or hospitalisation after a tracheal intubation episode. Cox regression analysis examined associations between the primary endpoint and healthcare worker characteristics, procedure-related factors and personal protective equipment use. Between 23 March and 2 June 2020, 1718 healthcare workers from 503 hospitals in 17 countries reported 5148 tracheal intubation episodes. The overall incidence of the primary endpoint was 10.7% over a median (IQR [range]) follow-up of 32 (18-48 [0-116]) days. The cumulative incidence within 7, 14 and 21 days of the first tracheal intubation episode was 3.6%, 6.1% and 8.5%, respectively. The risk of the primary endpoint varied by country and was higher in women, but was not associated with other factors. Around 1 in 10 healthcare workers involved in tracheal intubation of patients with suspected or confirmed COVID-19 subsequently reported a COVID-19 outcome. This has human resource implications for institutional capacity to deliver essential healthcare services, and wider societal implications for COVID-19 transmission.
  • |*Betacoronavirus [MESH]
  • |*Health Personnel [MESH]
  • |*Intubation, Intratracheal [MESH]
  • |Adult [MESH]
  • |COVID-19 [MESH]
  • |Coronavirus Infections/epidemiology/*transmission [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Occupational Exposure/*adverse effects [MESH]
  • |Pandemics [MESH]
  • |Pneumonia, Viral/epidemiology/*transmission [MESH]
  • |Proportional Hazards Models [MESH]
  • |Prospective Studies [MESH]
  • |Risk [MESH]


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