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2020 ; 30
(11
): 6178-6185
Nephropedia Template TP
gab.com Text
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English Wikipedia
Early chest CT features of patients with 2019 novel coronavirus (COVID-19)
pneumonia: relationship to diagnosis and prognosis
#MMPMID32518987
Chen HJ
; Qiu J
; Wu B
; Huang T
; Gao Y
; Wang ZP
; Chen Y
; Chen F
Eur Radiol
2020[Nov]; 30
(11
): 6178-6185
PMID32518987
show ga
OBJECTIVE: To determine the consistency between CT findings and real-time reverse
transcription-polymerase chain reaction (RT-PCR) and to investigate the
relationship between CT features and clinical prognosis in COVID-19. METHODS: The
clinical manifestations, laboratory parameters, and CT imaging findings were
analyzed in 34 COVID-19 patients, confirmed by RT-PCR from January 20 to February
4 in Hainan Province. CT scores were compared between the discharged patients and
the ICU patients. RESULTS: Fever (85%) and cough (79%) were most commonly seen.
Ten (29%) patients demonstrated negative results on their first RT-PCR. Of the 34
(65%) patients, 22 showed pure ground-glass opacity. Of the 34 (50%) patients, 17
had five lobes of lung involvement, while the 23 (68%) patients had lower lobe
involvement. The lesions of 24 (71%) patients were distributed mainly in the
subpleural area. The initial CT lesions of ICU patients were distributed in both
the subpleural area and centro-parenchyma (80%), and the lesions were scattered.
Sixty percent of ICU patients had five lobes involved, while this was seen in
only 25% of the discharged patients. The lesions of discharged patients were
mainly in the subpleural area (75%). Of the discharged patients, 62.5% showed
pure ground-glass opacities; 80% of the ICU patients were in the progressive
stage, and 75% of the discharged patients were at an early stage. CT scores of
the ICU patients were significantly higher than those of the discharged patients.
CONCLUSION: Chest CT plays a crucial role in the early diagnosis of COVID-19,
particularly for those patients with a negative RT-PCR. The initial features in
CT may be associated with prognosis. KEY POINTS: ? Chest CT is valuable for the
early diagnosis of COVID-19, particularly for those patients with a negative
RT-PCR. ? The early CT findings of COVID-19 in ICU patients differed from those
of discharged patients.