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2020 ; 42
(7
): 1583-1590
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gab.com Text
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Objective olfactory evaluation of self-reported loss of smell in a case series of
86 COVID-19 patients
#MMPMID32437033
Lechien JR
; Cabaraux P
; Chiesa-Estomba CM
; Khalife M
; Hans S
; Calvo-Henriquez C
; Martiny D
; Journe F
; Sowerby L
; Saussez S
Head Neck
2020[Jul]; 42
(7
): 1583-1590
PMID32437033
show ga
OBJECTIVE: To investigate olfactory dysfunction (OD) in patients with mild
coronavirus disease 2019 (COVID-19) through patient-reported outcome
questionnaires and objective psychophysical testing. METHODS: COVID-19 patients
with self-reported sudden-onset OD were recruited. Epidemiological and clinical
data were collected. Nasal complaints were evaluated with the sinonasal
outcome-22. Subjective olfactory and gustatory status was evaluated with the
National Health and Nutrition Examination Survey. Objective OD was evaluated
using psychophysical tests. RESULTS: Eighty-six patients completed the study. The
most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction
(58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by
61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12
hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation
between the objective test results and subjective reports of nasal obstruction or
postnasal drip. CONCLUSION: A significant proportion of COVID-19 patients
reporting OD do not have OD on objective testing.