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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Med+Virol
2020 ; 92
(11
): 2551-2555
Nephropedia Template TP
gab.com Text
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English Wikipedia
Effects of methylprednisolone use on viral genomic nucleic acid negative
conversion and CT imaging lesion absorption in COVID-19 patients under 50 years
old
#MMPMID32441786
Gong Y
; Guan L
; Jin Z
; Chen S
; Xiang G
; Gao B
J Med Virol
2020[Nov]; 92
(11
): 2551-2555
PMID32441786
show ga
The use of corticosteroids has been controversial in viral pneumonia. In most
cases, application of methylprednisolone in severe and critical viral pneumonia
patients can quickly alleviate the symptoms of dyspnea and prevent disease
progression. However, some scholars have confirmed that corticosteroids delayed
the body's clearance of the virus. In our retrospective non-randomized study, 34
patients under 50 years old and diagnosed with coronavirus disease 2019
(COVID-19) were included. According to the given methylprednisolone treatment
(n?=?18) or not (n?=?16), they were separated into two groups. By comparing the
clinical data we concluded that corticosteroids therapy can effectively release
COVID-19 symptoms such as persistent fever and difficult in breathing, improve
oxygenation, and prevent disease progression. However, it can prolong the
negative conversion of nucleic acids.