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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Pediatr+Gastroenterol+Nutr
2020 ; 70
(6
): 727-733
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global
Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto
Group of European Society of Paediatric Gastroenterology, Hepatology, and
Nutrition
#MMPMID32443020
Turner D
; Huang Y
; Martín-de-Carpi J
; Aloi M
; Focht G
; Kang B
; Zhou Y
; Sanchez C
; Kappelman MD
; Uhlig HH
; Pujol-Muncunill G
; Ledder O
; Lionetti P
; Dias JA
; Ruemmele FM
; Russell RK
J Pediatr Gastroenterol Nutr
2020[Jun]; 70
(6
): 727-733
PMID32443020
show ga
INTRODUCTION: With the current coronavirus disease 2019 (COVID-19) pandemic,
concerns have been raised about the risk to children with inflammatory bowel
diseases (IBD). We aimed to collate global experience and provide provisional
guidance for managing paediatric IBD (PIBD) in the era of COVID-19. METHODS: An
electronic reporting system of children with IBD infected with SARS-CoV-2 has
been circulated among 102 PIBD centres affiliated with the Porto and
Interest-group of ESPGHAN. A survey has been completed by major PIBD centres in
China and South-Korea to explore management during the pandemic. A third survey
collected current practice of PIBD treatment. Finally, guidance points for
practice have been formulated and voted upon by 37 PIBD authors and Porto group
members. RESULTS: Eight PIBD children had COVID-19 globally, all with mild
infection without needing hospitalization despite treatment with immunomodulators
and/or biologics. No cases have been reported in China and South Korea but
biologic treatment has been delayed in 79 children, of whom 17 (22%) had
exacerbation of their IBD. Among the Porto group members, face-to-face
appointments were often replaced by remote consultations but almost all did not
change current IBD treatment. Ten guidance points for clinicians caring for PIBD
patients in epidemic areas have been endorsed with consensus rate of 92% to 100%.
CONCLUSIONS: Preliminary data for PIBD patients during COVID-19 outbreak are
reassuring. Standard IBD treatments including biologics should continue at
present through the pandemic, especially in children who generally have more
severe IBD course on one hand, and milder SARS-CoV-2 infection on the other.