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2020 ; 4
(5
): 842-847
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Venous thromboembolism in critically Ill patients with COVID-19: Results of a
screening study for deep vein thrombosis
#MMPMID32685893
Longchamp A
; Longchamp J
; Manzocchi-Besson S
; Whiting L
; Haller C
; Jeanneret S
; Godio M
; Garcia Martinez JJ
; Bonjour T
; Caillat M
; Maitre G
; Thaler JM
; Pantet R
; Donner V
; Dumoulin A
; Emonet S
; Greub G
; Friolet R
; Robert-Ebadi H
; Righini M
; Sanchez B
; Delaloye J
Res Pract Thromb Haemost
2020[Jul]; 4
(5
): 842-847
PMID32685893
show ga
BACKGROUND: The rapid spread of the severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), and coronavirus disease 2019 (COVID-19), has caused more than 3.9
million cases worldwide. Currently, there is great interest to assess venous
thrombosis prevalence, diagnosis, prevention, and management in patients with
COVID-19. OBJECTIVES: To determine the prevalence of venous thromboembolism (VTE)
in critically ill patients with COVID-19, using lower limbs venous
ultrasonography screening. METHODS: Beginning March 8, we enrolled 25 patients
who were admitted to the intensive care unit (ICU) with confirmed SARS-CoV-2
infections. The presence of lower extremity deep vein thrombosis (DVT) was
systematically assessed by ultrasonography between day 5 and 10 after admission.
The data reported here are those available up to May 9, 2020. RESULTS: The mean
(± standard deviation) age of the patients was 68 ± 11 years, and 64% were men.
No patients had a history of VTE. During the ICU stay, 8 patients (32%) had a
VTE; 6 (24%) a proximal DVT, and 5 (20%) a pulmonary embolism. The rate of
symptomatic VTE was 24%, while 8% of patients had screen-detected DVT. Only those
patients with a documented VTE received a therapeutic anticoagulant regimen. As
of May 9, 2020, 5 patients had died (20%), 2 remained in the ICU (8%), and 18
were discharged (72%). CONCLUSIONS: In critically ill patients with SARS-CoV-2
infections, DVT screening at days 5-10 of admission yielded a 32% prevalence of
VTE. Seventy-five percent of events occurred before screening. Earlier screening
might be effective in optimizing care in ICU patients with COVID-19.