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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Gastrointest+Surg
2021 ; 25
(1
): 252-259
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Development and Validation of a Clinical Risk Score for Intensive Care Resource
Utilization After Colon Cancer Surgery: a Practical Guide to the Selection of
Patients During COVID-19
#MMPMID32495141
Garfinkle R
; Abou-Khalil M
; Salama E
; Marinescu D
; Pang A
; Morin N
; Demyttenaere S
; Liberman AS
; Vasilevsky CA
; Boutros M
J Gastrointest Surg
2021[Jan]; 25
(1
): 252-259
PMID32495141
show ga
BACKGROUND: The purpose of this study was to develop and validate a prediction
model and clinical risk score for Intensive Care Resource Utilization after colon
cancer surgery. METHODS: Adult (? 18 years old) patients from the 2012 to 2018
ACS-NSQIP colectomy-targeted database who underwent elective colon cancer surgery
were identified. A prediction model for 30-day postoperative Intensive Care
Resource Utilization was developed and transformed into a clinical risk score
based on the regression coefficients. Model performance was assessed using the
area under the receiver operating characteristic curve (AUC) and Hosmer-Lemeshow
goodness-of-fit test. The model was validated in a separate test set of similar
patients. RESULTS: In total, 54,893 patients underwent an elective colon cancer
resection, of which 1224 (2.2%) required postoperative Intensive Care Resource
Utilization. The final prediction model retained six variables: age (? 70; OR
1.90, 95% CI 1.68-2.14), sex (male; OR 1.73, 95% CI 1.54-1.95), American Society
of Anesthesiologists score (III/IV; OR 2.52, 95% CI 2.15-2.95), cardiorespiratory
disease (yes; OR 2.22, 95% CI 1.94-2.53), functional status (dependent; OR 2.81,
95% CI 2.22-3.56), and operative approach (open surgery; OR 1.70, 95% CI
1.51-1.93). The model demonstrated good discrimination (AUC = 0.73). A clinical
risk score was developed, and the risk of requiring postoperative Intensive Care
Resource Utilization ranged from 0.03 (0 points) to 19.0% (8 points). The model
performed well on test set validation (AUC = 0.73). CONCLUSION: A prediction
model and clinical risk score for postoperative Intensive Care Resource
Utilization after colon cancer surgery was developed and validated.
|*COVID-19
[MESH]
|*Colectomy
[MESH]
|*Patient Selection
[MESH]
|Adult
[MESH]
|Age Factors
[MESH]
|Aged
[MESH]
|Clinical Decision Rules
[MESH]
|Colonic Neoplasms/pathology/*surgery
[MESH]
|Comorbidity
[MESH]
|Critical Care/*statistics & numerical data
[MESH]
|Databases, Factual
[MESH]
|Elective Surgical Procedures
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Intensive Care Units/*statistics & numerical data
[MESH]