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2020 ; 35
(7
): 1410-1413
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The role of extracorporeal life support for patients with COVID-19: Preliminary
results from a statewide experience
#MMPMID32333431
Sultan I
; Habertheuer A
; Usman AA
; Kilic A
; Gnall E
; Friscia ME
; Zubkus D
; Hirose H
; Sanchez P
; Okusanya O
; Szeto WY
; Gutsche J
J Card Surg
2020[Jul]; 35
(7
): 1410-1413
PMID32333431
show ga
OBJECTIVE: There is a paucity of clinical data on critically ill patients with
COVID-19 requiring extracorporeal life support. METHODS: A statewide
multi-institutional collaborative for COVID-19 patients was utilized to obtain
clinical data on the first 10 critically ill COVID-19 patients who required
extracorporeal membrane oxygenation (ECMO). RESULTS: Of the first 10 patients
that required ECMO for COVID-19, the age ranged from 31 to 62 years with the
majority (70%) being men. Seven (70%) had comorbidities. The majority (80%) of
patients had known sick contact and exposure to COVID-19 positive patients or
traveled to pandemic areas inside the United States within the 2 weeks before
symptom onset. None of the patients were healthcare workers. The most common
symptoms leading to the presentation were high fever ?103°F (90%), cough (80%)
and dyspnea (70%), followed by fatigue and gastrointestinal symptoms (both 30%),
myalgia, loss of taste, pleuritic chest pain, and confusion (all 10%). All
patients had bilateral infiltrates on chest X-rays suggestive of interstitial
viral pneumonia. All patients were cannulated in the venovenous configuration.
Two (20%) patients were successfully liberated from ECMO support after 7 and 10
days, respectively, and one (10%) patient is currently on a weaning course. One
patient (10%) died after 9 days on ECMO from multiorgan dysfunction. CONCLUSIONS:
These preliminary multi-institutional data from a statewide collaborative offer
insight into the clinical characteristics of the first 10 patients requiring ECMO
for COVID-19 and their initial clinical course. Greater morbidity and mortality
is likely to be seen in these critically ill patients with longer follow-up.
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