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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Dermatol+Ther
2020 ; 33
(4
): e13508
Nephropedia Template TP
gab.com Text
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COVID-19 knowledge prevents biologics discontinuation: Data from an Italian
multicenter survey during RED-ZONE declaration
#MMPMID32415727
Bragazzi NL
; Riccò M
; Pacifico A
; Malagoli P
; Kridin K
; Pigatto P
; Damiani G
Dermatol Ther
2020[Jul]; 33
(4
): e13508
PMID32415727
show ga
SARS-CoV-2 become pandemics and there is still a dearth of data about its the
potentially among dermatological patients under biologics. We aimed to assess
health literacy, disease knowledge, treatment dissatisfaction and biologics
attitudes toward COVID-19. We performed a cross-sectional, questionnaire-based
survey on 98/105 consecutive dermatological patients treated with biologics-51
suffering from plaque psoriasis, 22 from atopic dermatitis, and 25 from
hidradenitis suppurativa. An ad hoc, validated questionnaire has 44 items
investigating the following domains: knowledge of COVID-19 related to (a)
epidemiology, (b) pathogenesis, (c) clinical symptoms, (d) preventive measures,
and (e) attitudes. Patients data and questionnaires were collected. Despite only
8.1% thought that biologics may increase the risk of COVID-19, 18.4% and 21.4% of
the patients were evaluating the possibility to discontinue or modify the dosage
of the current biologic therapy, respectively. Globally, male patients (P = .001)
with higher scholarity level (P = .005) displayed higher knowledge of COVID-19.
Patients with lower DLQI (P = .006), longer disease duration (P = .051) and lower
scholarity (P = .007) have thought to discontinue/modify autonomously their
biologic therapy. At the multivariate logistic regression, only the knowledge of
epidemiology and preventive measures resulted independent predictors of
continuation vs discontinuation and modification vs no modification,
respectively. Dermatologists should promote COVID-19 knowledge to prevent
biologics disruption.