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10.1002/pmic.202000107 http://scihub22266oqcxt.onion/10.1002/pmic.202000107 C7267140!7267140 !32462744     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32462744 &cmd=llinks): Failed to open stream: HTTP request failed! 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Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimental Data-Dependent Acquisition Tandem Mass Spectrometry Data |pdf=|usr=}}{{32462744 }} gab.com Text Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimental Data-Dependent Acquisition Tandem Mass Spectrometry Data JO: Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32462744 #FOAvip Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a crucial tool for fighting the COVID-19 pandemic. This dataset brief presents the exploration of a shotgun proteomics dataset acquired on SARS-CoV-2 infected Vero cells. Proteins from inactivated virus samples were extracted, digested with trypsin, and the resulting peptides were identified by data-dependent acquisition tandem mass spectrometry. The 101 peptides reporting for six viral proteins were specifically analyzed in terms of their analytical characteristics, species specificity and conservation, and their proneness to structural modifications. Based on these results, a shortlist of 14 peptides from the N, S, and M main structural proteins that could be used for targeted mass-spectrometry method development and diagnostic of the new SARS-CoV-2 is proposed and the best candidates are commented. Twit Text FOAVip Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimental Data-Dependent Acquisition Tandem Mass Spectrometry Data ????Proteomics http://www.kidney.de/pget.php?&tw=1&pmid=32462744 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32462744 #FOAvip English Wikipedia <ref>{{Cite pmid|32462744 }}</ref> Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimental Data-Dependent Acquisition Tandem Mass Spectrometry Data #MMPMID32462744 Gouveia D ; Grenga L ; Gaillard JC ; Gallais F ; Bellanger L ; Pible O ; Armengaud J Proteomics 2020[Jul]; 20 (14 ): e2000107 PMID32462744 show ga Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a crucial tool for fighting the COVID-19 pandemic. This dataset brief presents the exploration of a shotgun proteomics dataset acquired on SARS-CoV-2 infected Vero cells. Proteins from inactivated virus samples were extracted, digested with trypsin, and the resulting peptides were identified by data-dependent acquisition tandem mass spectrometry. The 101 peptides reporting for six viral proteins were specifically analyzed in terms of their analytical characteristics, species specificity and conservation, and their proneness to structural modifications. Based on these results, a shortlist of 14 peptides from the N, S, and M main structural proteins that could be used for targeted mass-spectrometry method development and diagnostic of the new SARS-CoV-2 is proposed and the best candidates are commented. |Amino Acid Sequence [MESH] |Animals [MESH] |Betacoronavirus/*chemistry/isolation & purification [MESH] |COVID-19 [MESH] |Chlorocebus aethiops [MESH] |Coronavirus Infections/diagnosis/*virology [MESH] |Humans [MESH] |Pandemics [MESH] |Peptides/*analysis [MESH] |Pneumonia, Viral/diagnosis/*virology [MESH] |Proteomics [MESH] |SARS-CoV-2 [MESH] |Tandem Mass Spectrometry [MESH] |Vero Cells [MESH] |Viral Proteins/*analysis [MESH]Shortlisting SARS-CoV-2 Peptides for Targeted Studies from Experimenta(epmc).pdf DeepDyve Pubget Overpricing