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10.1016/j.arcmed.2020.05.024

http://scihub22266oqcxt.onion/10.1016/j.arcmed.2020.05.024
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C7261434!7261434!32536457
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suck abstract from ncbi


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pmid32536457      Arch+Med+Res 2020 ; 51 (7): 733-5
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  • Should We Try SARS-CoV-2 Helicase Inhibitors for COVID-19 Therapy? #MMPMID32536457
  • Habtemariam S; Nabavi SF; Banach M; Berindan-Neagoe I; Sarkar K; Sil PC; Nabavi SM
  • Arch Med Res 2020[Oct]; 51 (7): 733-5 PMID32536457show ga
  • The discovery of new drugs for treating the new coronavirus (SARS-CoV-2) or repurposing those already in use for other viral infections is possible through understanding of the viral replication cycle and pathogenicity. This article highlights the advantage of targeting one of the non-structural proteins, helicase (nsp13), over other SARS-CoV-2 proteins. Highlighting the experience gained from targeting Nsp13 in similar coronaviruses (SARS-CoV and MERS) and known inhibitors, the article calls for research on helicase inhibitors as potential COVID-19 therapy.
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