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10.1016/j.mehy.2020.109858

http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.109858
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suck abstract from ncbi


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pmid32516655
      Med+Hypotheses 2020 ; 143 (ä): 109858
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  • Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent #MMPMID32516655
  • Pindiprolu SKSS ; Kumar CSP ; Kumar Golla VS ; P L ; K SC ; S K EB ; R K R
  • Med Hypotheses 2020[Oct]; 143 (ä): 109858 PMID32516655 show ga
  • Coronavirus disease outbreak caused a severe public health burden all over the world. Salinomycin (SAL) is a broad-spectrum antibiotic that had drawn attention in selective targeting of cancer and viral infections. Recent drug screen identified SAL as a potent antiviral agent against SARS-CoV-2. In this hypothesis, we discuss the potential of pulmonary delivery of SAL using nanostructured lipid carriers (NLCs) against SARS-CoV-2.
  • |*Drug Carriers [MESH]
  • |Antiviral Agents/*administration & dosage [MESH]
  • |Betacoronavirus [MESH]
  • |COVID-19 [MESH]
  • |COVID-19 Drug Treatment [MESH]
  • |Coronavirus Infections/*drug therapy [MESH]
  • |Drug Repositioning [MESH]
  • |Endocytosis [MESH]
  • |Humans [MESH]
  • |Lipids/*chemistry [MESH]
  • |Lung/drug effects [MESH]
  • |Nanostructures/*chemistry [MESH]
  • |Pandemics [MESH]
  • |Pneumonia, Viral/*drug therapy [MESH]
  • |Pyrans/*administration & dosage [MESH]
  • |RNA, Viral [MESH]


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