Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32471884
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMJ
2020 ; 369
(ä): m1996
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Characterization and clinical course of 1000 patients with coronavirus disease
2019 in New York: retrospective case series
#MMPMID32471884
Argenziano MG
; Bruce SL
; Slater CL
; Tiao JR
; Baldwin MR
; Barr RG
; Chang BP
; Chau KH
; Choi JJ
; Gavin N
; Goyal P
; Mills AM
; Patel AA
; Romney MS
; Safford MM
; Schluger NW
; Sengupta S
; Sobieszczyk ME
; Zucker JE
; Asadourian PA
; Bell FM
; Boyd R
; Cohen MF
; Colquhoun MI
; Colville LA
; de Jonge JH
; Dershowitz LB
; Dey SA
; Eiseman KA
; Girvin ZP
; Goni DT
; Harb AA
; Herzik N
; Householder S
; Karaaslan LE
; Lee H
; Lieberman E
; Ling A
; Lu R
; Shou AY
; Sisti AC
; Snow ZE
; Sperring CP
; Xiong Y
; Zhou HW
; Natarajan K
; Hripcsak G
; Chen R
BMJ
2020[May]; 369
(ä): m1996
PMID32471884
show ga
OBJECTIVE: To characterize patients with coronavirus disease 2019 (covid-19) in a
large New York City medical center and describe their clinical course across the
emergency department, hospital wards, and intensive care units. DESIGN:
Retrospective manual medical record review. SETTING:
NewYork-Presbyterian/Columbia University Irving Medical Center, a quaternary care
academic medical center in New York City. PARTICIPANTS: The first 1000
consecutive patients with a positive result on the reverse transcriptase
polymerase chain reaction assay for severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) who presented to the emergency department or were admitted to
hospital between 1 March and 5 April 2020. Patient data were manually abstracted
from electronic medical records. MAIN OUTCOME MEASURES: Characterization of
patients, including demographics, presenting symptoms, comorbidities on
presentation, hospital course, time to intubation, complications, mortality, and
disposition. RESULTS: Of the first 1000 patients, 150 presented to the emergency
department, 614 were admitted to hospital (not intensive care units), and 236
were admitted or transferred to intensive care units. The most common presenting
symptoms were cough (732/1000), fever (728/1000), and dyspnea (631/1000).
Patients in hospital, particularly those treated in intensive care units, often
had baseline comorbidities including hypertension, diabetes, and obesity.
Patients admitted to intensive care units were older, predominantly male
(158/236, 66.9%), and had long lengths of stay (median 23 days, interquartile
range 12-32 days); 78.0% (184/236) developed acute kidney injury and 35.2%
(83/236) needed dialysis. Only 4.4% (6/136) of patients who required mechanical
ventilation were first intubated more than 14 days after symptom onset. Time to
intubation from symptom onset had a bimodal distribution, with modes at three to
four days, and at nine days. As of 30 April, 90 patients remained in hospital and
211 had died in hospital. CONCLUSIONS: Patients admitted to hospital with
covid-19 at this medical center faced major morbidity and mortality, with high
rates of acute kidney injury and inpatient dialysis, prolonged intubations, and a
bimodal distribution of time to intubation from symptom onset.
|Academic Medical Centers/statistics & numerical data
[MESH]