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2020 ; 36
(ä): 101751
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Efficacy of face mask in preventing respiratory virus transmission: A systematic
review and meta-analysis
#MMPMID32473312
Liang M
; Gao L
; Cheng C
; Zhou Q
; Uy JP
; Heiner K
; Sun C
Travel Med Infect Dis
2020[Jul]; 36
(ä): 101751
PMID32473312
show ga
BACKGROUND: Conflicting recommendations exist related to whether masks have a
protective effect on the spread of respiratory viruses. METHODS: The Preferred
Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement was
consulted to report this systematic review. Relevant articles were retrieved from
PubMed, Web of Science, ScienceDirect, Cochrane Library, and Chinese National
Knowledge Infrastructure (CNKI), VIP (Chinese) database. RESULTS: A total of 21
studies met our inclusion criteria. Meta-analyses suggest that mask use provided
a significant protective effect (OR = 0.35 and 95% CI = 0.24-0.51). Use of masks
by healthcare workers (HCWs) and non-healthcare workers (Non-HCWs) can reduce the
risk of respiratory virus infection by 80% (OR = 0.20, 95% CI = 0.11-0.37) and
47% (OR = 0.53, 95% CI = 0.36-0.79). The protective effect of wearing masks in
Asia (OR = 0.31) appeared to be higher than that of Western countries
(OR = 0.45). Masks had a protective effect against influenza viruses (OR = 0.55),
SARS (OR = 0.26), and SARS-CoV-2 (OR = 0.04). In the subgroups based on different
study designs, protective effects of wearing mask were significant in cluster
randomized trials and observational studies. CONCLUSIONS: This study adds
additional evidence of the enhanced protective value of masks, we stress that the
use masks serve as an adjunctive method regarding the COVID-19 outbreak.