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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Res+Cardiol
2020 ; 109
(12
): 1446-1459
Nephropedia Template TP
gab.com Text
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English Wikipedia
Coronavirus Disease 2019 (COVID-19) and its implications for cardiovascular care:
expert document from the German Cardiac Society and the World Heart Federation
#MMPMID32462267
Böhm M
; Frey N
; Giannitsis E
; Sliwa K
; Zeiher AM
Clin Res Cardiol
2020[Dec]; 109
(12
): 1446-1459
PMID32462267
show ga
Coronavirus diseases 2019 (COVID-19) has become a worldwide pandemic affecting
people at high risk and particularly at advanced age, cardiovascular and
pulmonary disease. As cardiovascular patients are at high risk but also have
dyspnea and fatigue as leading symptoms, prevention, diagnostics and treatment in
these patients are important to provide adequate care for those with or without
COVID-19 but most importantly when comorbid cardiovascular conditions are
present. Severe COVID-19 with acute respiratory distress (ARDS) is challenging as
patients with elevated myocardial markers such as troponin are at enhanced high
risk for fatal outcomes. As angiotensin-converting enzyme 2 (ACE2) is regarded as
the viral receptor for cell entry and as the Coronavirus is downregulating this
enzyme, which provides cardiovascular and pulmonary protection, there is ongoing
discussions on whether treatment with cardiovascular drugs, which upregulate the
viral receptor ACE2 should be modified. As most of the COVID-19 patients have
cardiovascular comorbidities like hypertension, diabetes, coronary artery disease
and heart failure, which imposes a high risk on these patients, cardiovascular
therapy should not be modified or even withdrawn. As cardiac injury is a common
feature of COVID-19 associated ARDS and is linked with poor outcomes, swift
diagnostic management and specialist care of cardiovascular patients in the area
of COVID-19 is of particular importance and deserves special attention.