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10.1177/0194599820931805 http://scihub22266oqcxt.onion/10.1177/0194599820931805 C7251624!7251624 !32452739     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32452739 &cmd=llinks): Failed to open stream: HTTP request failed! 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Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations |pdf=|usr=}}{{32452739 }} gab.com Text Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations JO: Otolaryngol Head Neck Surg http://www.kidney.de/pget.php?&tw=1&pmid=32452739 #FOAvip OBJECTIVE: In the era of SARS-CoV-2, the risk of infectious airborne aerosol generation during otolaryngologic procedures has been an area of increasing concern. The objective of this investigation was to quantify airborne aerosol production under clinical and surgical conditions and examine efficacy of mask mitigation strategies. STUDY DESIGN: Prospective quantification of airborne aerosol generation during surgical and clinical simulation. SETTING: Cadaver laboratory and clinical examination room. SUBJECTS AND METHODS: Airborne aerosol quantification with an optical particle sizer was performed in real time during cadaveric simulated endoscopic surgical conditions, including hand instrumentation, microdebrider use, high-speed drilling, and cautery. Aerosol sampling was additionally performed in simulated clinical and diagnostic settings. All clinical and surgical procedures were evaluated for propensity for significant airborne aerosol generation. RESULTS: Hand instrumentation and microdebridement did not produce detectable airborne aerosols in the range of 1 to 10 ?m. Suction drilling at 12,000 rpm, high-speed drilling (4-mm diamond or cutting burs) at 70,000 rpm, and transnasal cautery generated significant airborne aerosols (P < .001). In clinical simulations, nasal endoscopy (P < .05), speech (P < .01), and sneezing (P < .01) generated 1- to 10-?m airborne aerosols. Significant aerosol escape was seen even with utilization of a standard surgical mask (P < .05). Intact and VENT-modified (valved endoscopy of the nose and throat) N95 respirator use prevented significant airborne aerosol spread. CONCLUSION: Transnasal drill and cautery use is associated with significant airborne particulate matter production in the range of 1 to 10 ?m under surgical conditions. During simulated clinical activity, airborne aerosol generation was seen during nasal endoscopy, speech, and sneezing. Intact or VENT-modified N95 respirators mitigated airborne aerosol transmission, while standard surgical masks did not. Twit Text FOAVip Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations ????Otolaryngol Head Neck Surg http://www.kidney.de/pget.php?&tw=1&pmid=32452739 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32452739 #FOAvip English Wikipedia <ref>{{Cite pmid|32452739 }}</ref> Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID-19: Risks and Recommendations #MMPMID32452739 Workman AD ; Jafari A ; Welling DB ; Varvares MA ; Gray ST ; Holbrook EH ; Scangas GA ; Xiao R ; Carter BS ; Curry WT ; Bleier BS Otolaryngol Head Neck Surg 2020[Sep]; 163 (3 ): 465-470 PMID32452739 show ga OBJECTIVE: In the era of SARS-CoV-2, the risk of infectious airborne aerosol generation during otolaryngologic procedures has been an area of increasing concern. The objective of this investigation was to quantify airborne aerosol production under clinical and surgical conditions and examine efficacy of mask mitigation strategies. STUDY DESIGN: Prospective quantification of airborne aerosol generation during surgical and clinical simulation. SETTING: Cadaver laboratory and clinical examination room. SUBJECTS AND METHODS: Airborne aerosol quantification with an optical particle sizer was performed in real time during cadaveric simulated endoscopic surgical conditions, including hand instrumentation, microdebrider use, high-speed drilling, and cautery. Aerosol sampling was additionally performed in simulated clinical and diagnostic settings. All clinical and surgical procedures were evaluated for propensity for significant airborne aerosol generation. RESULTS: Hand instrumentation and microdebridement did not produce detectable airborne aerosols in the range of 1 to 10 ?m. Suction drilling at 12,000 rpm, high-speed drilling (4-mm diamond or cutting burs) at 70,000 rpm, and transnasal cautery generated significant airborne aerosols (P < .001). In clinical simulations, nasal endoscopy (P < .05), speech (P < .01), and sneezing (P < .01) generated 1- to 10-?m airborne aerosols. Significant aerosol escape was seen even with utilization of a standard surgical mask (P < .05). Intact and VENT-modified (valved endoscopy of the nose and throat) N95 respirator use prevented significant airborne aerosol spread. CONCLUSION: Transnasal drill and cautery use is associated with significant airborne particulate matter production in the range of 1 to 10 ?m under surgical conditions. During simulated clinical activity, airborne aerosol generation was seen during nasal endoscopy, speech, and sneezing. Intact or VENT-modified N95 respirators mitigated airborne aerosol transmission, while standard surgical masks did not. |*Otorhinolaryngologic Surgical Procedures [MESH] |Aerosols/*adverse effects [MESH] |Betacoronavirus [MESH] |COVID-19 [MESH] |Cadaver [MESH] |Coronavirus Infections/*transmission [MESH] |Endoscopy [MESH] |Humans [MESH] |Nose/*virology [MESH] |Pandemics [MESH] |Particle Size [MESH] |Personal Protective Equipment [MESH] |Pneumonia, Viral/*transmission [MESH] |Prospective Studies [MESH] |Risk Factors [MESH]Airborne Aerosol Generation During Endonasal Procedures in the Era of (epmc).pdf DeepDyve Pubget Overpricing