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2020 ; 129
(ä): 109092
Nephropedia Template TP
gab.com Text
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English Wikipedia
Diagnostic impact of bedside chest X-ray features of 2019 novel coronavirus in
the routine admission at the emergency department: case series from Lombardy
region
#MMPMID32485335
Ippolito D
; Pecorelli A
; Maino C
; Capodaglio C
; Mariani I
; Giandola T
; Gandola D
; Bianco I
; Ragusi M
; Talei Franzesi C
; Corso R
; Sironi S
Eur J Radiol
2020[Aug]; 129
(ä): 109092
PMID32485335
show ga
PURPOSE: To evaluate the diagnostic accuracy and the imaging features of routine
admission chest X-ray in patients suspected for novel Coronavirus 2019
(SARS-CoV-2) infection. METHOD: We retrospectively evaluated clinical and X-ray
features in all patients referred to the emergency department for suspected
SARS-CoV-2 infection between March 1st and March 13th. A single radiologist with
more than 15 years of experience in chest-imaging evaluated the presence and
extent of alveolar opacities, reticulations, and/or pleural effusion. The
percentage of lung involvement (range <25 % to 75-100 %) was also calculated. We
stratified patients in groups according to the time interval between symptoms
onset and X-ray imaging (? 5 and > 5 days) and according to age (? 50 and > 50
years old). RESULTS: A total of 518 patients were enrolled. Overall 314 patients
had negative and 204 had positive RT-PCR results. Lung lesions in patients with
SARS-Cov2 pneumonia primarily manifested as alveolar and interstitial opacities
and were mainly bilateral (60.8 %). Lung abnormalities were more frequent and
more severe by symptom duration and by increasing age. The sensitivity and
specificity of chest X-ray at admission in the overall cohort were 57 % (95 %
CI?=?47-67) and 89 % (83-94), respectively. Sensitivity was higher for patients
with symptom onset > 5 days compared to ? 5 days (76 % [62-87] vs 37 % [24-52])
and in patients > 50 years old compared to ? 50 years (59 % [48-69] vs 47 %
[23-72]), at the expense of a slightly lower specificity (68 % [45-86] and 82 %
[73-89], respectively). CONCLUSIONS: Overall chest X-ray sensitivity for
SARS-CoV-2 pneumonia was 57 %. Sensitivity was higher when symptoms had started
more than 5 days before, at the expense of lesser specificity, while slightly
higher in older patients in comparison to younger ones.