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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2020 ; 99
(21
): e20370
Nephropedia Template TP
gab.com Text
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English Wikipedia
CT manifestations of the coronavirus disease 2019 of imported infection versus
second-generation infection in patients outside the original district (Wuhan,
China) of this disease: An observational study
#MMPMID32481333
Wu YP
; Cao JM
; Chen TW
; Li R
; Liu FJ
; Zeng Y
; Zhang XM
; Mu QW
; Li HJ
Medicine (Baltimore)
2020[May]; 99
(21
): e20370
PMID32481333
show ga
To explore the discrepancy in computed tomography (CT) manifestations of the
coronavirus disease 2019 (COVID-19) in patients outside the original district
(Wuhan, China) between cases with imported infection and second-generation
infection, 22 patients with COVID-19 from 2 hospitals in Nanchong, China, 938 km
away from the original district (Wuhan, China) of this disease were enrolled. All
patients underwent initial and follow-up CT after admission during the treatment,
and were divided into 2 groups. Group A and B were composed of 15 patients with a
history of exposure to the original district (Wuhan, China) in short-term (i.e.,
imported infection), and 7 with a close contact with the patients with confirmed
COVID-19 or with the healthy individuals from the original district (i.e.,
second-generation infection), respectively. Initial CT features including extent
score and density score between groups were statistically compared. We found that
all patients in group A and 3 of 7 patients in group B had abnormal CT findings
while 4 of 7 patients in group B had not. Patients with abnormal CT findings were
more frequent in group A than in group B (P?.05). On initial CT, pure ground
glass opacity (GGO), and GGO with consolidation and/or other abnormalities were
found in 20% (3/15) and 80% (12/15) patients in group A, respectively, while 1
(14.3%), 2 (28.6%), and 4 (57.1%) had pure GGOs, GGO with focal consolidation,
and normal CT appearances in Group B, respectively. Patients with extent and
density scores of ?5 were more frequent in group A than in group B (all
P-values?.01). Additionally, 3 of 4 (75%) patients with normal initial CT
findings had focal pure GGO lesions on follow-up. In conclusion, COVID-19 in
patients with a history of exposure to the original district can be severer than
with the second-generation infection on CT.