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2020 ; 59
(5
): 102820
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19)
using convalescent plasma
#MMPMID32467007
Kong Y
; Cai C
; Ling L
; Zeng L
; Wu M
; Wu Y
; Zhang W
; Liu Z
Transfus Apher Sci
2020[Oct]; 59
(5
): 102820
PMID32467007
show ga
BACKGROUND: Because treatment options for coronavirus disease 2019 (COVID-19) are
very limited, the use of convalescent plasma has bee explored. CASE PRESENTATION
AND TREATMENT: A male centenarian with cough and dyspnea for 2 months was
diagnosed with COVID-19. Without effective treatments and with the increased
risks of antiviral therapy for the elderly, this patient was given convalescent
plasma. The viral load, complete blood count, inflammatory indicators, vital
signs, and clinical symptoms were observed before and after COVID-19 convalescent
plasma transfusion. RESULTS: After convalescent plasma transfusion, significant
improvement was observed on laboratory indicators and clinical symptoms of the
patient. Concurrently, SARS-CoV-2 viral load decreased sharply after the first
transfusion (from 2.55 × 104 to 1.39 × 103 copies/mL) and became undetectable
after the second transfusion. CONCLUSIONS: With the substantial increase of
COVID-19 in recent months,treatment for elderly patients has become restricted in
some countries. The successful treatment of this 100-year-old patient using
convalescent plasma suggests that we should consider adding convalescent plasma
in th management of the elderly.