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2020 ; 14
(5
): e0008280
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
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English Wikipedia
Clinical findings of patients with coronavirus disease 2019 in Jiangsu province,
China: A retrospective, multi-center study
#MMPMID32384078
Huang R
; Zhu L
; Xue L
; Liu L
; Yan X
; Wang J
; Zhang B
; Xu T
; Ji F
; Zhao Y
; Cheng J
; Wang Y
; Shao H
; Hong S
; Cao Q
; Li C
; Zhao XA
; Zou L
; Sang D
; Zhao H
; Guan X
; Chen X
; Shan C
; Xia J
; Chen Y
; Yan X
; Wei J
; Zhu C
; Wu C
PLoS Negl Trop Dis
2020[May]; 14
(5
): e0008280
PMID32384078
show ga
Limited data are available for clinical characteristics of patients with
coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe
the clinical characteristics of COVID-19 and identify the risk factors for severe
illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized
COVID-19 patients were retrospectively collected in 8 hospitals from 8 cities of
Jiangsu province, China. Clinical findings of COVID-19 patients were described
and risk factors for severe illness of COVID-19 were analyzed. By Feb 10, 2020,
202 hospitalized patients with COVID-19 were enrolled. The median age of patients
was 44.0 years (interquartile range, 33.0-54.0). 55 (27.2%) patients had
comorbidities. At the onset of illness, the common symptoms were fever (156
[77.2%]) and cough (120 [59.4%]). 66 (32.7%) patients had lymphopenia. 193
(95.5%) patients had abnormal radiological findings. 11 (5.4%) patients were
admitted to the intensive care unit and none of the patients died. 23 (11.4%)
patients had severe illness. Severe illness of COVID-19 was independently
associated with body mass index (BMI) ? 28 kg/m2 (odds ratio [OR], 9.219; 95%
confidence interval [CI], 2.731 to 31.126; P<0.001) and a known history of type 2
diabetes (OR, 4.326; 95% CI, 1.059 to 17.668; P = 0.041). In this case series in
Jiangsu Province, COVID-19 patients had less severe symptoms and had better
outcomes than the initial COVID-19 patients in Wuhan. The BMI ? 28 kg/m2 and a
known history of type 2 diabetes were independent risk factors of severe illness
in patients with COVID-19.