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2020 ; 71
(16
): 2187-2190
Nephropedia Template TP
gab.com Text
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English Wikipedia
Coronavirus Disease 2019 (COVID-19) Clinical Trial Oversight at a Major Academic
Medical Center: Approach of Michigan Medicine
#MMPMID32392334
Spector-Bagdady K
; Higgins PDR
; Aaronson KD
; Birk J
; Flaherty KR
; Gregg KS
; Hyzy RC
; Kaul DR
; Lauring AS
; Magee JC
; Meurer WJ
; Park PK
; Scott P
; Lok AS
Clin Infect Dis
2020[Nov]; 71
(16
): 2187-2190
PMID32392334
show ga
Clinicians, eager to offer the best care in the absence of guiding data, have
provided patients with coronavirus disease 2019 (COVID-19) diverse clinical
interventions. This usage has led to perceptions of efficacy of some
interventions that, while receiving media coverage, lack robust evidence. Moving
forward, randomized controlled clinical trials are necessary to ensure that
clinicians can treat patients effectively during this outbreak and the next. To
do so, academic medical centers must address 2 key research issues: (1) how to
effectively and efficiently determine which trials have the best chance of
benefiting current and future patients and (2) how to establish a transparent and
ethical process for subject recruitment while maintaining research integrity and
without overburdening patients or staff. We share here the current methods used
by Michigan Medicine to address these issues.
|*Academic Medical Centers
[MESH]
|COVID-19/*therapy
[MESH]
|Humans
[MESH]
|Informed Consent
[MESH]
|Michigan
[MESH]
|Patient Selection/*ethics
[MESH]
|Randomized Controlled Trials as Topic/*standards
[MESH]