Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32382737
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32382737
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Infect+Dis
2020 ; 222
(2
): 189-193
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
A Peptide-Based Magnetic Chemiluminescence Enzyme Immunoassay for Serological
Diagnosis of Coronavirus Disease 2019
#MMPMID32382737
Cai XF
; Chen J
; Li Hu J
; Long QX
; Deng HJ
; Liu P
; Fan K
; Liao P
; Liu BZ
; Wu GC
; Chen YK
; Li ZJ
; Wang K
; Zhang XL
; Tian WG
; Xiang JL
; Du HX
; Wang J
; Hu Y
; Tang N
; Lin Y
; Ren JH
; Huang LY
; Wei J
; Gan CY
; Chen YM
; Gao QZ
; Chen AM
; He CL
; Wang DX
; Hu P
; Zhou FC
; Huang AL
; Wang DQ
J Infect Dis
2020[Jun]; 222
(2
): 189-193
PMID32382737
show ga
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel
?-coronavirus, causes severe pneumonia and has spread throughout the globe
rapidly. The disease associated with SARS-CoV-2 infection is named coronavirus
disease 2019 (COVID-19). To date, real-time reverse-transcription polymerase
chain reaction (RT-PCR) is the only test able to confirm this infection. However,
the accuracy of RT-PCR depends on several factors; variations in these factors
might significantly lower the sensitivity of detection. METHODS: In this study,
we developed a peptide-based luminescent immunoassay that detected immunoglobulin
(Ig)G and IgM. The assay cutoff value was determined by evaluating the sera from
healthy and infected patients for pathogens other than SARS-CoV-2. RESULTS: To
evaluate assay performance, we detected IgG and IgM in the sera from confirmed
patients. The positive rate of IgG and IgM was 71.4% and 57.2%, respectively.
CONCLUSIONS: Therefore, combining our immunoassay with real-time RT-PCR might
enhance the diagnostic accuracy of COVID-19.