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10.1016/j.biopha.2020.110265 http://scihub22266oqcxt.onion/10.1016/j.biopha.2020.110265 C7233259!7233259 !32425327     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32425327 &cmd=llinks): Failed to open stream: HTTP request failed! 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Evaluation of the synergetic effect of Yupingfeng san and Flos Sophorae Immaturus based on free radical scavenging capacity |pdf=|usr=}}{{32425327 }} gab.com Text Evaluation of the synergetic effect of Yupingfeng san and Flos Sophorae Immaturus based on free radical scavenging capacity JO: Biomed Pharmacother http://www.kidney.de/pget.php?&tw=1&pmid=32425327 #FOAvip OBJECTIVE: This study aimed to determine the optimal extraction process and examine whether the combination of Flos Sophorae Immaturus (FSI) and Yupingfeng san (YPS) has a synergistic effect on free radical scavenging capacity. DESIGN AND METHODS: The time of immersion and extraction and the ratios (material/solvent) of the combination of YPS and FSI were optimized on the basis of polysaccharide and flavonoid yields via orthogonal design. The optimal result was used in the 1,1-diphenyl-1-picrylhydrazyl (DPPH) assay and animal experiments to test the antioxidant activity, which is reflected by superoxide dismutase, malondialdehyde, glutathione peroxidase, and total antioxidant capacity serum levels. The optimal extraction process was determined using various ingredients to obtain complex extracts with high active ingredient content and antioxidant activity. DPPH assay results showed that the optimized ingredients have antioxidant effects, and the combination had better antioxidation function than YPS in vitro. The combination also showed synergistic antioxidant activity compared with YPS in vivo. CONCLUSIONS: The combination of YPS and FSI had a synergistic antioxidant effect in vitro. The optimized extracts had antioxidant effects in vivo. These results indicated that YPS could be used with FSI to improve its antioxidant capacity in the body on the basis of free radical scavenging capacity. Twit Text FOAVip Evaluation of the synergetic effect of Yupingfeng san and Flos Sophorae Immaturus based on free radical scavenging capacity ????Biomed Pharmacother http://www.kidney.de/pget.php?&tw=1&pmid=32425327 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32425327 #FOAvip English Wikipedia <ref>{{Cite pmid|32425327 }}</ref> Evaluation of the synergetic effect of Yupingfeng san and Flos Sophorae Immaturus based on free radical scavenging capacity #MMPMID32425327 Huang R ; Zhang Y ; Zhang Y ; Zhang L ; Pei L ; Shu G ; Yuan Z ; Lin J ; Peng G ; Zhang W ; Zhao L ; Shi F ; Fu H Biomed Pharmacother 2020[Aug]; 128 (ä): 110265 PMID32425327 show ga OBJECTIVE: This study aimed to determine the optimal extraction process and examine whether the combination of Flos Sophorae Immaturus (FSI) and Yupingfeng san (YPS) has a synergistic effect on free radical scavenging capacity. DESIGN AND METHODS: The time of immersion and extraction and the ratios (material/solvent) of the combination of YPS and FSI were optimized on the basis of polysaccharide and flavonoid yields via orthogonal design. The optimal result was used in the 1,1-diphenyl-1-picrylhydrazyl (DPPH) assay and animal experiments to test the antioxidant activity, which is reflected by superoxide dismutase, malondialdehyde, glutathione peroxidase, and total antioxidant capacity serum levels. The optimal extraction process was determined using various ingredients to obtain complex extracts with high active ingredient content and antioxidant activity. DPPH assay results showed that the optimized ingredients have antioxidant effects, and the combination had better antioxidation function than YPS in vitro. The combination also showed synergistic antioxidant activity compared with YPS in vivo. CONCLUSIONS: The combination of YPS and FSI had a synergistic antioxidant effect in vitro. The optimized extracts had antioxidant effects in vivo. These results indicated that YPS could be used with FSI to improve its antioxidant capacity in the body on the basis of free radical scavenging capacity. |Administration, Oral [MESH] |Animals [MESH] |Biomarkers/blood [MESH] |Biphenyl Compounds/chemistry [MESH] |Drug Synergism [MESH] |Drugs, Chinese Herbal/administration & dosage/*pharmacology [MESH] |Free Radical Scavengers/administration & dosage/*pharmacology [MESH] |Glutathione Peroxidase/blood [MESH] |Male [MESH] |Malondialdehyde/blood [MESH] |Mice [MESH] |Picrates/chemistry [MESH]Evaluation of the synergetic effect of Yupingfeng san and Flos Sophora(epmc).pdf DeepDyve Pubget Overpricing