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2020 ; 40
(4
): 606-608
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Prevention and control of SARS-CoV-2 infection in clinical laboratories:
implementation of contingency plan and postpandemic response strategies
#MMPMID32895124
Hang J
; Sun Z
; Li L
Nan Fang Yi Ke Da Xue Xue Bao
2020[Apr]; 40
(4
): 606-608
PMID32895124
show ga
The outbreak of COVID-19 has currently been under control in China, but now the
disease has rapidly evolved into a global pandemic. We formulated a prevention
and control plan for clinical laboratories responsible for detection of the novel
coronavirus infection. We analyzed the implementation of this plan and the
problems arising from its clinical practice. We found that the layout of most
clinical laboratories (including gene amplification laboratories for clinical
samples) was inadequate in response to a major outbreak and did not meet the
requirements for biosafety protection and etiology and serology testing; and
laboratory staff showed insufficiencies in their awareness regarding biosafety
protection; the functions and status of the laboratory in the fever clinic need
to be enhanced to increase its detection capacity; the high density of military
personnel, the low level of automation of clinical laboratory equipment, and the
lack of biosafety cabinets and personal protective equipment all limit the
performance of diverse military operations and major overseas missions. In view
of these problems, we propose the following strategies and recommendations: the
clinical laboratory needs to standardize the design and staff management
according to the standards of P2 laboratory; the detection capacity and staffing
of fever clinic laboratory in hospitals need to be strengthened, and a separate
clinical gene amplification laboratory can be optimal; for those clinical gene
amplification laboratories that fail to meet these standards, reconstruction and
upgrade should be made according to the requirements of biosafety protection; for
the clinical laboratory in the military medical system, in addition to
enforcement of biological safety protection of the staff, sufficient supply of
medical materials and biological safety equipment should be ensured and
biological safety cabinets should be routinely equipped if possible.
|*Betacoronavirus
[MESH]
|*Coronavirus Infections/prevention & control
[MESH]