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2020 ; 22
(6-7
): 245-253
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for
coronavirus vaccine development
#MMPMID32437926
Ma C
; Su S
; Wang J
; Wei L
; Du L
; Jiang S
Microbes Infect
2020[Jul]; 22
(6-7
): 245-253
PMID32437926
show ga
The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and
HCoV-19) has posed serious threats to public health and economic stability
worldwide, thus calling for development of vaccines against SARS-CoV-2 and other
emerging and reemerging coronaviruses. Since SARS-CoV-2 and SARS-CoV have high
similarity of their genomic sequences and share the same cellular receptor
(ACE2), it is essential to learn the lessons and experiences from the development
of SARS-CoV vaccines for the development of SARS-CoV-2 vaccines. In this review,
we summarized the current knowledge on the advantages and disadvantages of the
SARS-CoV vaccine candidates and prospected the strategies for the development of
safe, effective and broad-spectrum coronavirus vaccines for prevention of
infection by currently circulating SARS-CoV-2 and other emerging and reemerging
coronaviruses that may cause future epidemics or pandemics.
|Animals
[MESH]
|Betacoronavirus/genetics
[MESH]
|COVID-19
[MESH]
|COVID-19 Vaccines
[MESH]
|Coronavirus Infections/classification/immunology/*prevention & control
[MESH]
|Cross Protection
[MESH]
|Humans
[MESH]
|Pandemics/*prevention & control
[MESH]
|Pneumonia, Viral/immunology/*prevention & control
[MESH]
|SARS-CoV-2
[MESH]
|Severe Acute Respiratory Syndrome/immunology/*prevention & control
[MESH]