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10.1021/acschemneuro.0c00217

http://scihub22266oqcxt.onion/10.1021/acschemneuro.0c00217
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C7192347!7192347!32348111
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suck abstract from ncbi


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pmid32348111      ACS+Chem+Neurosci ä ; ä (ä): ä
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  • Is the Collapse of the Respiratory Center in the Brain Responsible for Respiratory Breakdown in COVID-19 Patients? #MMPMID32348111
  • Gandhi S; Srivastava AK; Ray U; Tripathi PP
  • ACS Chem Neurosci ä[]; ä (ä): ä PMID32348111show ga
  • Following the identification of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, we are now again facing a global highly pathogenic novel coronavirus (SARS-CoV-2) epidemic. Although the lungs are one of the most critically affected organs, several other organs, including the brain may also get infected. Here, we have highlighted that SARS-CoV-2 might infect the central nervous system (CNS) through the olfactory bulb. From the olfactory bulb, SARS-CoV-2 may target the deeper parts of the brain including the thalamus and brainstem by trans-synaptic transfer described for many other viral diseases. Following this, the virus might infect the respiratory center of brain, which could be accountable for the respiratory breakdown of COVID-19 patients. Therefore, it is important to screen the COVID-19 patients for neurological symptoms as well as possibility of the collapse of the respiratory center in the brainstem should be investigated in depth.
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