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10.1007/s00706-020-02584-8

http://scihub22266oqcxt.onion/10.1007/s00706-020-02584-8
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C7186117!7186117!32346184
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suck abstract from ncbi


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pmid32346184      Monatsh+Chem 2020 ; 151 (4): 605-10
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  • Assembling the prenylneoflavone system through a Pechmann condensation/Mitsunobu reaction/Claisen rearrangement/olefin cross-metathesis sequence #MMPMID32346184
  • Lozinski OA; Bistodeau J; Bennetau-Pelissero C; Khilya VP; Shinkaruk S
  • Monatsh Chem 2020[]; 151 (4): 605-10 PMID32346184show ga
  • Abstract: The multistep synthesis of a prenylneoflavone through a sequence of the Mitsunobu reaction/Claisen rearrangement/olefin cross-metathesis reaction has been accomplished in 5% yield over six steps starting from commercially available 3-methoxyacetophenone. The sequence is shown to be compatible with a Pechmann condensation which proved to be a robust and cost-effective method for the assembling of the ?-pyrone core. The results open doors to a general approach to the prenylneoflavone system starting from phenol and acetophenone derivatives. Graphic abstract: Electronic supplementary material: The online version of this article (10.1007/s00706-020-02584-8) contains supplementary material, which is available to authorized users.
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