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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Reumatol+Clin 2021 ; 17 (6): 309-12 Nephropedia Template TP
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Propuesta de uso de anakinra en el distrés respiratorio agudo secundario a COVID-19 #MMPMID38620280
Muñoz-Jiménez A; Rubio-Romero E; Marenco de la Fuente JL
Reumatol Clin 2021[Jun]; 17 (6): 309-12 PMID38620280show ga
The outcome of the SARS-CoV-2 (COVID-19) infection fundamentally affects the lung field, causing acute respiratory distress syndrome (ARDS). This process is an inflammatory picture, involving an NLRP3 inflamosome-triggered cytokine storm, the main player in alveolar destruction. IL-1 beta stands out among the cytokines that are triggered in this picture. Anakinra is a potent biological drug, capable of blocking this IL-1ß. We propose its use in controlling ARDS secondary to COVID-19 infection.