Pros and cons of the application of evolutionary theories to the evolution of
SARS-CoV-2
#MMPMIDC7175784
Li Y
; Yang X
; Wang N
; Wang H
; Yin B
; Yang X
; Jiang W
Future Virol
2020[Apr]; ? (?): ? PMIDC7175784
show ga
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused severe damage to the world. With the support of classic evolutionary
theories and population genetics principles, many studies on the origin of
SARS-CoV-2 have revealed encouraging results but meanwhile some are still under
debate. We are concerned with the validity of applying classic evolutionary
theories and formula to the evolution of RNA viruses. We have raised several
confounding factors like the RNA replication feature and the RNA modification
systems of the hosts, which might jeopardize the validity of the application of
classic methods to analyze the SARS-CoV-2 data.