Promising methods for detection of novel coronavirus SARS-CoV-2
#MMPMID38607796
Liu R
; Fu A
; Deng Z
; Li Y
; Liu T
View (Beijing)
2020[Mar]; 1
(1
): e4
PMID38607796
show ga
A very recent outbreak of the novel coronavirus, COVID-19, in the city of Wuhan,
China, in December 2019 and its subsequent spread within and across China have
resulted in several deaths and infections. Presently, nucleic acid amplification
test is essential for the confirmation of COVID infection. In this report, we
summarized the six promising methods, including whole-genome sequencing,
real-time reverse transcription polymerase chain reaction, nanopore target
sequencing, antibody-based immunoassay techniques, use of paper-based
biomolecular sensors, and the clustered regularly interspaced short palindromic
repeats-Cas system-based technology, which can also be deployed for the detection
of SARS-CoV-2. We further introduced the principles of these methods, discussed
the scope and practicability of application of the available products and
methods, and highlighted the potential approaches to develop additional products
and techniques for early diagnosis of COVID-19.
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