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10.1111/pai.12565 http://scihub22266oqcxt.onion/10.1111/pai.12565 C7167905!7167905 !26999792     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26999792 &cmd=llinks): Failed to open stream: HTTP request failed! 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Non-immediate hypersensitivity reactions to beta-lactam antibiotics in children - our 10-year experience in allergy work-up |pdf=|usr=}}{{26999792 }} gab.com Text Non-immediate hypersensitivity reactions to beta-lactam antibiotics in children - our 10-year experience in allergy work-up JO: Pediatr Allergy Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26999792 #FOAvip BACKGROUND: Non-immediate reactions to beta-lactam antibiotics (BL) occur more than one hour after drug administration, and the most common manifestations are maculopapular exanthemas and delayed-appearing urticaria and/or angioedema. Infections can lead to skin eruptions and mimic drug hypersensitivity reactions (DHR), if a drug is taken at the same time. The most of children are labeled as 'drug allergic' after considering only the clinical history. OBJECTIVE: To diagnose/detect a hypersensitivity or an infection which mimic DHR in children with non-immediate reactions to BL METHODS: A prospective survey was conducted in a group of 1026 children with histories of non-immediate reactions to BL by performing patch tests, skin tests, and in case of negative results, drug provocation tests (DPTs). In 300 children, a study was performed to detect infections by viruses or Mycoplasma pneumoniae. RESULTS: Urticaria and maculopapular exanthemas were the most reported non-immediate reactions. Only 76 (7.4%) of 1026 children had confirmed non-immediate hypersensitivity reactions to BL. Fifty-seven children had positive delayed-reading intradermal tests (18 of these with a positive patch test). Nineteen children had positive DPT. Sixty-six of 300 children had positive tests for viruses or Mycoplasma pneumoniae and 2 of them had a positive allergy work-up. CONCLUSIONS: A diagnostic work-up should be performed in all children with non-immediate reactions to BL, to remove a false label of hypersensitivity. Even though only 57 (5.5%) of 1026 children displayed positive responses to delayed-reading intradermal tests to BL, such tests appear to be useful in order to reduce the risk for positive DPTs. Twit Text FOAVip Non-immediate hypersensitivity reactions to beta-lactam antibiotics in children - our 10-year experience in allergy work-up ????Pediatr Allergy Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26999792 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26999792 #FOAvip English Wikipedia <ref>{{Cite pmid|26999792 }}</ref> Non-immediate hypersensitivity reactions to beta-lactam antibiotics in children - our 10-year experience in allergy work-up #MMPMID26999792 Atanaskovic-Markovic M ; Gaeta F ; Medjo B ; Gavrovic-Jankulovic M ; Cirkovic Velickovic T ; Tmusic V ; Romano A Pediatr Allergy Immunol 2016[Aug]; 27 (5 ): 533-8 PMID26999792 show ga BACKGROUND: Non-immediate reactions to beta-lactam antibiotics (BL) occur more than one hour after drug administration, and the most common manifestations are maculopapular exanthemas and delayed-appearing urticaria and/or angioedema. Infections can lead to skin eruptions and mimic drug hypersensitivity reactions (DHR), if a drug is taken at the same time. The most of children are labeled as 'drug allergic' after considering only the clinical history. OBJECTIVE: To diagnose/detect a hypersensitivity or an infection which mimic DHR in children with non-immediate reactions to BL METHODS: A prospective survey was conducted in a group of 1026 children with histories of non-immediate reactions to BL by performing patch tests, skin tests, and in case of negative results, drug provocation tests (DPTs). In 300 children, a study was performed to detect infections by viruses or Mycoplasma pneumoniae. RESULTS: Urticaria and maculopapular exanthemas were the most reported non-immediate reactions. Only 76 (7.4%) of 1026 children had confirmed non-immediate hypersensitivity reactions to BL. Fifty-seven children had positive delayed-reading intradermal tests (18 of these with a positive patch test). Nineteen children had positive DPT. Sixty-six of 300 children had positive tests for viruses or Mycoplasma pneumoniae and 2 of them had a positive allergy work-up. CONCLUSIONS: A diagnostic work-up should be performed in all children with non-immediate reactions to BL, to remove a false label of hypersensitivity. Even though only 57 (5.5%) of 1026 children displayed positive responses to delayed-reading intradermal tests to BL, such tests appear to be useful in order to reduce the risk for positive DPTs. |Adolescent [MESH] |Allergens/immunology [MESH] |Child [MESH] |Child, Preschool [MESH] |Diagnosis, Differential [MESH] |Exanthema/*diagnosis [MESH] |Female [MESH] |Humans [MESH] |Hypersensitivity, Delayed/*diagnosis [MESH] |Infant [MESH] |Male [MESH] |Mycoplasma pneumoniae/*physiology [MESH] |Pneumonia, Mycoplasma/*diagnosis [MESH] |Prospective Studies [MESH] |Skin Tests [MESH] |Urticaria/*diagnosis [MESH] |Virus Diseases/*diagnosis [MESH]Non-immediate hypersensitivity reactions to beta-lactam antibiotics in(epmc).pdf DeepDyve Pubget Overpricing