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10.1002/jmv.23538

http://scihub22266oqcxt.onion/10.1002/jmv.23538
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C7167083!7167083!23508913
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suck abstract from ncbi


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pmid23508913      J+Med+Virol 2013 ; 85 (5): 874-9
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  • Use of the human colorectal adenocarcinoma (Caco?2) cell line for isolating respiratory viruses from nasopharyngeal aspirates? #MMPMID23508913
  • Chan K; Yan M; To K; Lau S; Woo P; Cheng V; Li W; Chan J; Tse H; Yuen K
  • J Med Virol 2013[May]; 85 (5): 874-9 PMID23508913show ga
  • The human colorectal adenocarcinoma?derived Caco?2 cell line was evaluated as a means isolating common respiratory viruses from nasopharyngeal aspirates for the diagnosis of respiratory diseases. One hundred eighty?nine direct immunofluorescence positive nasopharyngeal aspirates obtained from patients with various viral respiratory diseases were cultured in the presence of Caco?2 cells or the following conventional cell lines: LLC?MK2, MDCK, HEp?2, and A549. Caco?2 cell cultures effectively propagated the majority (84%) of the viruses present in nasopharyngeal aspirate samples compared with any positive cultures obtained using the panel cells (78%) or individual cell line MDCK (38%), HEp?2 (21%), LLC?MK2 (27%), or A549 (37%) cell lines. The differences against individual cell line were statistically significant (P?=?
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